The most devious plan ever created in a Nicktoons world is unfolding. Professor Calamitous has pulled together Plankton; Vlad; and Crocker to form a group known as The Evil Syndicate. The wicked foursome have begun to wreak havoc throughout Retroville; Amity Park; Dimmsdale; and Bikini Bottom in an attempt to take over the world. Not to be outsmarted; Jimmy Neutron calls upon his own band of Nicktoons. Jimmy; Timmy; Danny; and SpongeBob SquarePants combine their powers to take out The Evil Syndicate along with the devastating Doomsday device. Its good versus evil where only one side will prevail.
- 1-4 player cooperative play featuring SpongeBob SquarePants Timmy Turner Jimmy Neutron or Danny Phantom
- More than 15 explorable Nicktoons levels including: Retroville Dimmsdale Amity Park and Bikini Bottom